Here is a program that I found useful and portable.
-From the site-
P2Wiz is p2p block lists downloader. It currently supports PhoenixLabs (PeerGuardian) and OpenMedia (IPFilter) block lists. This block lists support most popular p2p clients.
http://gravityfx.org/p2w
It writes all its settings in an ini file and does not change any system file/folder.
Hope you all like it.
My 2 cents.
Enjoy !!!
Jainendra